Legemiddel mot psykoser. I psykiatrien brukes benevnelsen antipsykotika synonymt med nevroleptika eller psykoleptika.
Angitt pris er maksimal utsalgspris fra apotek. Pakninger som selges uten resept er angitt med stjerne *. Det er fri prisfastsettelse for pakninger som selges uten resept, og maksimal utsalgspris kan derfor ikke angis.
Induksjon av metabolismen av paracetamol i lever, både til inaktive metabolitter og til den levertoksiske metabolitten NAPQI.
Animal and scientific research have decided that acetaminophen has both equally antipyretic and analgesic effects. This drug has become demonstrated to deficiency anti-inflammatory effects. Rather than the salicylate drug class, acetaminophen will not disrupt tubular secretion of uric acid and isn't going to affect acid-foundation harmony if taken for the advisable doses.
The percentage of a systemically absorbed rectal dose of acetaminophen is inconsistent, demonstrated by key distinctions during the bioavailability of acetaminophen following a dose administered rectally.
Thanks to its minimal hazard of creating allergic reactions, this drug might be administered in sufferers that are intolerant to salicylates and those with allergic tendencies, like bronchial asthmatics. Distinct dosing tips need to be adopted when administering acetaminophen to young children.
On account of the potential of fatal overdose and liver failure affiliated with the incorrect utilization of acetaminophen, it is necessary to adhere to latest and offered countrywide and producer dosing pointers while this drug is taken or prescribed.
Ingen mistanke om fosterskadelig effekt ved regular website dosering. Ved intoksikasjoner er det høy frekvens av fosterdød og spontanaborter
Higher rectal doses or an elevated frequency of administration can be accustomed to achieve blood concentrations of acetaminophen just like These attained after oral acetaminophen administration. Absorption
Induksjon av metabolismen av paracetamol i lever, både til inaktive metabolitter og til den levertoksiske metabolitten NAPQI.
. The antipyretic actions of acetaminophen are likely attributed to immediate motion on heat-regulating facilities while in the Mind, resulting in peripheral vasodilation, perspiring, and lack of human body warmth. The exact mechanism of motion of the drug just isn't absolutely understood right now, but future investigation may perhaps contribute to further understanding. Codeine can be a selective agonist with the mu opioid receptor, but with a A lot weaker affinity to this receptor than morphine, a more strong opioid drug.
a. i celleveggene hvor de formidler et bestemt signal når en bestemt substans binder seg til reseptoren. Dette signalet kan da hemmes ved bruk av en antagonist som bindes til samme reseptor.
For sentralt godkjente legemidler ligger alle styrker og legemiddelformer etter hverandre i samme dokument.
Overdose and liver toxicity Acetaminophen overdose could be manifested by renal tubular necrosis, hypoglycemic coma, and thrombocytopenia. Occasionally, liver necrosis can occur and liver failure.
In scientific studies performed through the National Toxicology Method, fertility assessments are carried out in Swiss mice in a ongoing breeding review. No consequences on fertility ended up noticed. Use in pregnancy and nursing
Et syndrom som kjennetegnes av svikt i det CNS i forbindelse med leversvikt. Symptomer er blant annet tiredness og forvirring som ofte forverres til koma, tremor i hender og øye- og muskelrykninger.